四溴双酚A对赤子爱胜蚓的急性毒性及抗氧化防御系统酶的影响Acute Toxicity of Tetrabromobisphenol A to Earthworms Eisenia fetida and Its Effects on Antioxidant Defense System Enzymes
薛银刚;王晓蓉;顾雪元;孙成;
摘要(Abstract)：
以赤子爱胜蚓(Eisenia fetida)为研究对象,根据OECD指南中的滤纸接触法和人工土壤法研究了四溴双酚A(TBBPA)的急性毒性和对蚯蚓体内抗氧化防御系统酶的影响.结果表明,滤纸接触法和人工土壤法检测TBBPA对蚯蚓的半致死浓度LC50分别为4.90mg·L-(148h)和16.7mg·kg-(114d),TBBPA对蚯蚓具有低等毒性.当TBBPA的浓度在0.05和0.1mg·kg-1时对蚯蚓超氧化物歧化酶(SOD)产生显著诱导;在0.05mg·kg-1时,对过氧化氢酶(CAT)和谷胱甘肽硫转移酶(GST)也产生显著诱导;脂质过氧化产物丙二醛(MDA)随TBBPA浓度的升高逐渐增加,呈良好的剂量效应关系(R2=0.97,p<0.01).SOD、CAT、GST和MDA可以作为土壤生态早期预警中潜在的敏感的生物标志物.
关键词(KeyWords)： 四溴双酚A;赤子爱胜蚓;急性毒性;抗氧化防御系统
基金项目(Foundation): 国家自然科学基金项目(No.20577021)
作者(Author): 薛银刚;王晓蓉;顾雪元;孙成;
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