胎盘内多环芳烃分布及源解析研究Distribution and Source Apportionment of Polycyclic Aromatic Hydrocarbon in Human Placentas
陈晓;艾芳;吴敏;彭娟;董旭东;
摘要(Abstract):
探讨多环芳烃在胎盘中的分布,并对其进行源解析。从2012年6月—2013年6月在云南省第一人民医院产科分娩的产妇中随机抽取30例,利用气相色谱-质谱联用仪(GC-MS)检测其胎盘中多环芳烃的含量;比较胎盘的中央部分和边缘部分多环芳烃含量的差异;对多环芳烃进行源解析,探讨其主要来源。胎盘中检测到多种多环芳烃成分;其中2~4个苯环的多环芳烃占总量的90%以上,尤其是萘、苊、芴、菲、蒽、芘、荧蒽的含量较高;萘、苊烯、苊、茚并(1,2,3-c,d)芘、二苯并(a,h)蒽5种多环芳烃在胎盘中央的含量高于边缘,具有显著性差异(P<0.05),其他多环芳烃在胎盘中央和边缘的含量无显著性差异(P>0.05)。多环芳烃源解析提示80%研究对象体内的多环芳烃主要来自石油产品的燃烧或暴露于石油产品。
关键词(KeyWords): 多环芳烃;胎盘;分布;源解析
基金项目(Foundation): 国家自然科学基金项目(41361086);; 云南省联合专项(2012FB091);; 云南省中青年学术和技术带头人后备人才资助项目(2008PY045);; 云南省科技厅重点项目(2014FA046)
作者(Author): 陈晓;艾芳;吴敏;彭娟;董旭东;
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DOI:
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