利用体外实验方法评估稻米中镉的生物可给性和健康风险Bioaccessiblity of Cadmium in Rice and Its Health Risk Assessment by In Vitro Method
徐笠;刘洋;杨婧婧;栾云霞;陆安祥;
摘要(Abstract):
为了研究稻米中镉(Cd)的生物可给性与稻米理化性质之间的相互关系以及稻米摄入而导致的Cd健康风险,从湖南某些地区采集了16个稻米样品,利用in vitro方法研究了这些稻米中Cd的生物可给性及其人体健康风险。结果表明:在16个样品中,有13个样品的Cd含量超过稻米中Cd的限量标准(0.2 mg·kg-1)。稻米中Cd的溶解态含量及其生物可给性变化较大,胃阶段和肠阶段Cd的溶解态含量范围分别为0.102~1.70 mg·kg-1和0.015~0.249 mg·kg-1,平均值分别为0.698 mg·kg-1和0.103 mg·kg-1,胃阶段和肠阶段Cd的生物可给性的范围分别为56.8%~82.0%和6.62%~15.9%,平均值分别为70.9%和11.1%。模拟肠液中Cd的溶解态含量与稻米的纤维含量之间有显著的相关性。如果不考虑稻米中Cd的生物可给性,所采集的所有稻米样品的摄入都将导致成人和儿童健康风险。如果我们考虑了稻米中的生物可给性,只有31%的稻米样品会对成人产生健康风险,将有50%的稻米样品会对儿童产生健康风险。
关键词(KeyWords): Cd;稻米;生物可给性;健康风险
基金项目(Foundation): 公益性行业(农业)科研专项(201403014-04);; 国家自然科学基金项目(41301551);; 江苏省自然科学基金项目(BK20130426);; 北京市农林科学院青年基金(QNJJ201717);北京市农林科学院创新能力建设项目(KJCX20180116)
作者(Author): 徐笠;刘洋;杨婧婧;栾云霞;陆安祥;
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