气溶胶中抗生素抗性基因研究进展:以养殖场和医院为例Progress in Research on Antibiotic Resistance Genes in Aerosols: Take Farms and Hospitals as Examples
薛银刚;刘菲;王利平;江晓栋;王倩;施昕澜;薛柯;金珊;姜逸;
摘要(Abstract):
抗生素在医药和养殖业的大量使用导致耐药菌的出现,加速了抗生素抗性基因(antibiotic resistance genes,ARGs)在不同环境介质中的传播扩散,抗生素耐药性已成为目前全球卫生、食品安全和发展的最大威胁之一。气溶胶作为ARGs的潜在储存库缺乏系统的研究数据,而通过空气传播具有较高抗生素抗性水平的细菌可能是引起重要疾病的主要传播途径。本文针对养殖场和医院2个抗生素大量使用的典型场所,对气溶胶中ARGs的污染现状、样品采集与检测技术进行综述,并探讨了这一环境污染的潜在风险,表明开展气溶胶中ARGs研究的必要性,并为以后需开展的工作提出几点建议。
关键词(KeyWords): 抗生素抗性基因;抗生素耐药性;气溶胶;养殖场;医院
基金项目(Foundation): 国家自然科学基金项目(21607016);; 常州市科技局科技支撑社会发展项目(CE20175022);; 环境基准与风险评估国家重点实验室开放课题(SKLECRA20160FP20);; 上海市大气颗粒物污染防治重点实验室开放课题(FDLAP17005)
作者(Author): 薛银刚;刘菲;王利平;江晓栋;王倩;施昕澜;薛柯;金珊;姜逸;
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DOI:
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