胡佳玥;戴家银;

• 1:中国科学院动物研究所
• 2:中国科学院动物生态与保护生物学重点实验室

摘要(Abstract)：

全氟和多氟烷酸类化合物(perfluoroalkyl and polyfluoroalkyl substances,PFASs)是一类新型持久性有机污染物,目前其在民用和工业产品中得到广泛应用。在环境样品、野生动物以及人类体内都检测到了这类物质。PFASs对哺乳动物和水生生物具有广泛的毒性,其对生态环境和人体健康的影响受到公众关注。目前,PFASs对人类健康的研究还多停留在流行病学研究和体外细胞毒性研究方面,由于人类有复杂的免疫和代谢系统,因此PPASs对人类健康影响的具体机制和安全剂量仍然需要进一步研究。本文针对PFASs在人体的分布、流行病学研究、毒理学效应和作用机制等热点问题进行了总结,并对目前PFASs研究存在的问题及今后的研究方向进行讨论和展望。

关键词(KeyWords)： 全氟和多氟烷酸类化合物;人类健康;流行病学研究;毒理学效应

Abstract:

Keywords:

基金项目(Foundation): 国家重点基础研究发展计划"973计划"(2013CB945204);; 国家自然科学基金(31025006)

作者(Author): 胡佳玥;戴家银;

Email:

DOI:

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