全氟辛烷磺酸神经发育毒性机制研究进展Research Progress on Mechanisms in the Developmental Neurotoxicity of PFOS
刘晓晖;胡宏;李双月;邵静;刘薇;金一和;
摘要(Abstract):
全氟辛烷磺酸(PFOS)是全氟化合物的终端降解产物,在生态环境中能够通过食物链进入生物组织并蓄积,对环境和生物存在潜在危害。动物实验研究发现,PFOS能够通过胎盘和血脑屏障,影响发育期神经系统,其持续性和严重性已引起国内外学者的广泛关注。本文通过对PFOS神经发育毒性效应及其主要机制研究进展进行综述,分析目前研究现状,并对未来PFOS神经发育毒性机制研究提出设想和展望。
关键词(KeyWords): PFOS;神经发育毒性;钙;神经递质;神经胶质细胞
基金项目(Foundation): 国家自然基金(81273031);; 大连医科大学引进人才科研启动基金(201069);; 大连理工大学工业生态与环境工程教育部重点实验室开放基金(KLIEEE-12-04)
作者(Author): 刘晓晖;胡宏;李双月;邵静;刘薇;金一和;
Email:
DOI:
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