无机砷在植物和微生物体内的代谢机制研究进展Recent Developments in Mechanisms of Arsenic Metabolism in Plants and Microbe
董晓玲;徐晓燕;
摘要(Abstract)：
砷污染是全球的热点问题之一.土壤中的无机砷在植物中的积累可通过食物链传递,从而对人体健康构成严重威胁.了解微生物和植物对无机砷的代谢机制,对认识和控制土壤中砷的风险至关重要.近年来,微生物对无机砷的代谢机制研究已经比较深入,但是仍有一些问题亟待解决,如信号传导、抗砷基因筛选等.在植物对无机砷的摄取、还原机制等方面也取得了一定进展,但是植物体内砷的转运机制、排出机制等仍有待进一步研究.论文综述了微生物、植物体内无机砷的代谢过程中,砷摄取、转运、还原和排出机制的最新进展,并对今后的研究方向进行了展望.
关键词(KeyWords)： 砷;摄取;还原;转运;区隔化;代谢;解毒
基金项目(Foundation): 铜陵市科技局资助项目(No.06FN1204)
作者(Author): 董晓玲;徐晓燕;
Email:
参考文献(References)：
- Abedin M J,Cresser M S,Meharg A A,Feldmann J,Cotter-Howells J.2002a.Arsenic accumulation and metabolism in rice(Oryza sativa L.)[J].Environmental Science&Technology,36:962-968
- Abedin M J,Feldmann J,Meharg A A.2002b.Uptake kineticsof arsenic species in rice plants[J].Plant Physiology,128:1120-1128
- Asher C J,Reay P F.1979.Arsenic uptake by barley seedlings[J].Australian Journal of Plant Physiology,6:459-466
- Berg M,Tran H C,Nguyen T C,Pham H V,Schertenleib R,Giger W.2001.Arsenic contamination of groundwater anddrinking water in Vietnam:a human health threa[tJ].EnvironmentalScience&Technology,35:2621-2626
- Bleeker P M,Hakvoort H W J,Bliek M,Souer E,Schat H.2006.Enhanced arsenate reduction by a CDC25-like tyrosinephosphatase explains increased phytochelatin accumulation inarsenate-tolerant Holcus lanatus[J].Plant Journal,45:917-929
- Bleeker P M,Schat H,Vooijs R,Verkleij J A C,Ernst W HO.2003.Mechanisms of arsenate tolerance in Cytisus striatus[J].New Phytologist,157:33-38
- Bun-ya M,Shikata K,Nakade S,Yompakdee C,Harashima S,Oshima Y.1996.Two new genes,PHO86and PHO87,involvedin inorganic phosphate uptake in Saccharomyces cerevisiae[J].Current Genetics,29:344-351
- Caille N,Zhao F J,McGrath S P.2005.Comparison of rootabsorption,translocation and tolerance of arsenic in thehyperaccumulator Pteris vittata and the nonhyperaccumulatorPteris tremula[J].New Phytologist,165:755-761
- Christen K.2001.The arsenic threat worsens[J].EnvironmentalScience&Technology,35:286A-291A
- Cobbett C S.2000.Phytochelatins and their roles in heavy metaldetoxification[J].Plant Physiology,123:825-832
- Dey S,Rosen B P.1995.Dual mode of energy coupling by theoxyanion-translocating ArsB protein[J].Journal of Bacteriology,177:385-389
- Dhankher O P.2005.Arsenic metabolism in plants:an insidestory[J].New Phytologist,168:503-505
- Dhankher O P,Rosen B P,McKinney E C,Meaqher R B.2006.Hyperaccumulation of arsenic in the shoots of Arabidopsis silencedfor arsenate reductase(ACR2)[J].Proceeding of the NationalAcademy of Sciences of the United States of America,103:5413-5418
- Duan G L,Wang L H,Chen Y,Meng X Y,Dong Y,Zhu YG.2007a.Recent developments in understanding the mechanismsof arsenic hyperaccumulation in plants[J].Acta ScientiaeCircumstantiae,27:714-720(in Chinese)
- Duan G L,Wang L H,Chen Y,Xu Y X,Meng X Y,Zhu YG.2007b.Health risk from consumption of rice with elevatedarsenic and studies of arsenic metabolism in rice[J].Journal ofAgro-Environment Science,26:430-435(in Chinese)
- Duan G L,Zhu Y G,Tong Y P,Cai C,Kneer R.2005.Characterization of arsenate reductase in the extract of roots andfronds of Chinese Brake Fern,an arsenic hyperaccumulator[J].Plant Physiology,138:461-469
- Ellis D R,Gumaelius L,Indriolo E,Pickering I J,Banks J ASalt D E.2006.A novel arsenate reductase from the arsenichyperaccumulating Pteris vittata[J].Plant Physiology,1411544-1554
- Hirano S,Kobayashi Y,Cui X,Kanno S,Hayakawa T,ShraimeA.2004.The accumulation and toxicity of methylated arsenicalsin endothelial cells:important roles of thiol compounds[J].Toxicology and Applied Pharmacology,198:458-467
- Hokura A,Omuna R,Terada Y,Kitajima N,Abe T,Saito H,Yoshida S,Nakai I.2006.Arsenic distribution and speciation inan arsenic hyperaccumulator fern by X-ray spectroscopy utilizinga synchrotron radiation source[J].Journal of Analytical AtomicSpectrometry,21:321-328
- Huang Z C,Chen T B,Lei M,Hu T D.2004.Directdetermination of arsenic species in arsenic hyperaccumulator Pterisvittata by EXAFS[J].Journal of Integrative Plant Biology,46:46-50(in Chinese)
- Ji G,Silver S.1992.Reduction of arsenate to arsenite by the AraC protein of the arsenic resistance operon of Staphylococcusaureus plasmid pI258[J].Proceeding of the National Academyof Sciences of the United States of America,89:9474-9478
- Koch I,Wang L X,Reimer K J,Cullen W R.2000.Arsenicspecies in terrestrial fungi and lichens from Yellowknife,NWT,Canada[J].Applied Organometallic Chemistry,14:245-252
- Lau W T,Howson R W,Malkus P,Schekman R,O’Shea EK.2000.Pho86p,an endoplasmic reticulum(ER)resident proteinin Saccharomyces cerevisiae,is required for ER exit of the high-affinity phosphate transporter Pho84p[J].Proceeding of theNational Academy of Sciences of the United States of America,97:1107-1112
- Li J,Rosen B P.2000.The linker peptide of the ArsA ATPase[J].Molecular Microbiology,35:361-367
- Lin Y F,Walmsley A R,Rosen B P.2006.An arsenicmetallochaperone for an arsenic detoxification pump[J].Proceeding of the National Academy of Sciences of the UnitedStates of America,103:15617-15622
- Liu W J,Zhu Y G,Hu Y,Williams P N,Gault A G,MehargA A,Charnock J M,Smith F A.2006.Arsenic sequestration iniron plaque,its accumulation and speciation in mature rice plants(Oryza sativa L.)[J].Environmental Science&Technology,40:5730-5736
- Ma J F,Yamaji N,Mitani N,Xu X Y,Su Y H,McGrath SP,Zhao F J.2008.Transporters of arsenite in rice and their rolein arsenic accumulation in rice grain[J].Proceeding of theNational Academy of Sciences of the United States of America,105:9931-9935
- Meharg A A,Jardine L.2003.Arsenite transport into paddy rice(Oryza sativa)roots[J].New Phytologist,157:39-44
- Meharg A A,Macnair M R.1992.Suppression of the highaffinity phosphate uptake system:a mechanism of arsenatetolerance in Holcus lanatus L.[J].Journal of ExperimentalBotany,43:519-524
- Mukhopadhyay R,Rosen B P.1998.Saccharomyces cerevisiaeACR2gene encodes an arsenate reductase[J].FEMS MicrobiologyLetters,168:127-136
- Nickson R,McArthur J,Burgess W,Ahmed M,Ravenscroft P,Rahman M.1998.Arsenic poisoning of Bangladesh groundwater[J].Nature,395:338
- Ordóez E,Letek M,Valbuena N,Gil J A,Mateos L M.2005.Analysis of genes involved in arsenic resistance in Corynebacteriumglutamicum ATCC13032[J].Applied and EnvironmentalMicrobiology,71:6206-6215
- Pickering I J,Gumaelius L,Harris H H,Prince R C,Hirsch G,Banks J A,Salt D E,George G N.2006.Localizing thebiochemical transformations of arsenate in a hyperaccumulatingfern[J].Environmental Science&Technology,40:5010-5014
- Quaghebeur M,Rengel Z.2004.Arsenic uptake,translocationand speciation in pho1and pho2mutants of Arabidopsis thaliana[J].Physiologia Plantarum,120:280-286
- Qin J,Rosen B P,Zhang Y,Wang G J,Franke S,Rensing C.2006.Arsenic detoxification and evolution of trimethylarsine gasby a microbial arsenite S-adenosylmethionine methyltransferase[J].Proceeding of the National Academy of Sciences of theUnited States of America,1037:2075-2080
- Raab A,Schat H,Meharg A A,Feldmann J.2005.Uptaketranslocation and transformation of arsenate and arsenite insunflower(Helianthus annuus):formation of arsenic-phytochelatincomplexes during exposure to high arsenic concentrations[J]New Phytologist,168:551-558
- Rahman M A,Hasegawa H,Ueda K,Maki T,Okumura C,Rahman M M.2007.Arsenic accumulation in duckweed(Spirodelapolyrhiza L.):a good option for phytoremediation[J].Chemosphere,69:493-499
- Reimann C,De Caritat P.1998.Chemical Elements in theEnvironment[M].Berlin:Springer
- Rosen B P.1999.Families of arsenic transporters[J].Trends inMicrobiology,7:207-212
- Rosen B P.2002.Biochemistry of arsenic detoxification[J].FEBS Letters,529:86-92
- Rosenberg H,Gerdes R G,Chegwidden K.1977.Two systemsfor the uptake of phosphate in Escherichia coli.[J].Journal ofBacteriology,131:505-511
- Tamás M J,Rep M,Thevelein J M,Hohmann S.2000.Stimulation of the yeast high osmolarity glycerol(HOG)pathway:evidence for a signal generated by a change in turgor rather thanby water stress[J].FEBS Letters,472:159-165
- Tripathi R D,Srivastava S,Mishra S,Singh N,Tuli R,GuptaD K,Maathuis F J M.2007.Arsenic hazards:strategies fortolerance and remediation by plants[J].Trends in Biotechnology,25:158-165
- Willsky G R,Malamy M H.1980.Effect of arsenate oninorganic phosphate transport in Escherichia coli.[J].Journal ofBacteriology,144:366-374
- Wu J,Tisa L S,Rosen B P.1992.Membrane topology of theArsB protein,the membrane subunit of an anion-translocatingATPase[J].Journal of Biological Chemistry,267:12570-12576
- Xu X Y,McGrath S P,Zhao F J.2007.Rapid reduction ofarsenate in the medium mediated by plant roots[J].NewPhytologist,176:590-599
- Zegers I,Martins J C,Willem R,Wyns L,Messens J.2001.Arsenate reductase from S.aureus plasmid pI258is a phosphatasedrafted for redox duty[J].Nature Structural Biology,8:843-847
- Zhao F J,Wang J R,Barker J H A,Schat H,Bleeker P M,McGrath S P.2003.The role of phytochelatins in arsenictolerance in the hyperaccumulator Pteris vittata[J].NewPhytologist,159:403-410
- Zhao R,Zhao M X,Wang H,Taneike Y,Zhang X R.2006.Arsenic speciation in moso bamboo shoot:a terrestrial plant thatcontains organoarsenic species[J].Science of the TotalEnvironment,371:293-303
- 段桂兰,王利红,陈玉,孟祥燕,董妍,朱永官.2007a.植物超富集砷机制研究的最新进展[J].环境科学学报,27:714-720
- 段桂兰,王利红,陈玉,徐玉新,孟祥燕,朱永官.2007b.水稻砷污染健康风险与砷代谢机制的研究[J].农业环境科学学报,26:430-435
- 黄泽春,陈同斌,雷梅,胡天斗.2004.超富集植物蜈蚣草中砷化学形态的EXAFS研究[J].植物学报,46:46-50