碳纳米管生殖毒性及其毒作用机制研究进展Research Progress on Reproductive Toxicity and the Toxic Mechanism of Carbon Nanotube
甘俊英;苏雪荣;薛玉英;李强;唐萌;
摘要(Abstract):
随着碳纳米管(carbon nanotubes,CNTs)在各个领域应用的增加,人们接触到CNTs的几率也随之增加,越来越多的人开始关注CNTs对于人体是否具有毒性及其毒性的大小,近些年的体内和体外研究显示,CNTs可对生物体(如小鼠、斑马鱼、赤子爱胜蚓等)生殖系统产生毒性并遗传给后代,影响后代生长发育。本综述主要从CNTs种类、官能化和CNTs悬浮液中团聚体尺寸及所含杂质3个方面探讨CNTs的生殖毒性及毒作用机制,以及影响其毒性及毒作用机制的因素,从而为CNTs更加安全有效的应用提供依据。
关键词(KeyWords): 碳纳米管;单壁碳纳米管;多壁碳纳米管;生殖毒性;多代毒性
基金项目(Foundation): 国家自然科学基金(81573186);; 江苏省普通高校研究生实践创新计划(SJCX17_0067,SJCX18_0078)
作者(Author): 甘俊英;苏雪荣;薛玉英;李强;唐萌;
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