韩绍伦;李剑;王子健;

• 1:北京师范大学水科学研究院地下水污染控制与修复教育部工程研究中心
• 2:中国科学院生态环境研究中心

摘要(Abstract)：

不断升高的糖尿病发病率在全球范围内引起广泛关注,流行病学调查显示糖尿病发病率的增加与环境内分泌干扰化合物使用量增大之间存在显著相关,环境内分泌干扰化合物可能增加糖尿病发病风险,是影响糖尿病的危险因素。在此背景下,综述了环境内分泌干扰化合物暴露与糖尿病发病之间的流行病学关系;环境内分泌干扰化合物暴露对胰岛β细胞胰岛素分泌的调节、高胰岛素效应及其潜在的作用机理,表明影响胰岛素分泌是环境内分泌干扰化合物调节代谢,诱发糖尿病的重要作用机制。

关键词(KeyWords)： 环境内分泌干扰物;作用机理;糖尿病;胰岛素;雌激素受体

Abstract:

Keywords:

基金项目(Foundation): 国家自然科学青年基金(41001351);; 高等学校博士学科点专项科研基金资助课题(20100003120024)

作者(Author): 韩绍伦;李剑;王子健;

Email:

参考文献(References)：

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