张瑾;刘树深;邓慧萍;周俊;王成林;

• 1:同济大学土木工程博士后流动站
• 2:同济大学环境科学与工程学院
• 3:长江水环境教育部重点实验室
• 4:安徽建筑大学环境与能源工程学院

摘要(Abstract)：

混合污染物产生的累积与毒性相互作用具有潜在的环境与健康风险。以6种吡啶类离子液体(IL):丁基溴化吡啶([Bpy]Br)、己基溴化吡啶([Hpy]Br)、辛基溴化吡啶([Opy]Br)、丁基氯化吡啶([Bpy]Cl)、己基氯化吡啶([Opy]Cl)和辛基氯化吡啶([Opy]Cl)为混合物组分,应用直接均分射线法(EquRay)和均匀设计射线法(UD-Ray)分别设计4组二元IL混合物和2组三元混合物,每组混合物包括5条具有不同浓度配比的混合物射线。应用微板毒性分析法测定6种IL及其30条混合物射线对青海弧菌Q67的发光抑制毒性,以浓度加和(CA)为加和参考模型分析混合物毒性相互作用。结果表明,Logit函数能有效地拟合6种吡啶IL及其30条混合物射线的浓度-效应数据。若以半数效应浓度的负对数(pEC50)为毒性指标,6个吡啶IL对Q67的毒性与烷基链上碳原子数目正相关,且每增加2个碳原子,其毒性约增加1。IL的阴离子(Br-或Cl-)对毒性没有影响。除己基氯化吡啶([Hpy]Cl)和辛基氯化吡啶([Opy]Cl)的二元混合物呈现明显拮抗作用外,其他二元及三元混合物都为加和作用。

关键词(KeyWords)： 吡啶类离子液体;青海弧菌Q67;微板毒性分析法;浓度加和;拮抗

Abstract:

Keywords:

基金项目(Foundation): 长江水环境教育部重点实验室开放课题(YRWEF201101);; 国家自然科学基金(21207002,20977065);; 安徽省住房和城乡建设部项目(No.416)

作者(Author): 张瑾;刘树深;邓慧萍;周俊;王成林;

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