刘帅;宿甜甜;刘长发;魏海峰;赵肖依;宋雪;

• 1:辽宁省近岸海洋环境科学与技术重点实验室
• 2:大连海洋大学海洋科技与环境学院
• 3:大连海洋大学农业农村部北方海水增养殖重点实验室

摘要(Abstract)：

为揭示不同种类多环芳烃(PAHs)污染物对中间球海胆(Strongylocentrotus intermedius)的生态毒理效应,研究了不同浓度的苯并(a)芘(1、5和20μg·L~(-1))以及2种烷基多环芳烃3-甲基菲(5、10和100μg·L~(-1))和2-甲基蒽(5、10和50μg·L~(-1))对海胆细胞色素CYP17A1基因表达的影响。结果表明,随着暴露时间的增加,不同浓度的3种多环芳烃对海胆细胞色素CYP17A1基因表达产生不同程度的影响。与对照组相比,暴露14 d后,苯并(a)芘20μg·L~(-1)处理组对海胆CYP17A1基因的表达表现出抑制作用(P<0.05);暴露14 d后,3-甲基菲100μg·L~(-1)处理组对海胆CYP17A1基因的表达表现出诱导作用(P<0.05);暴露14 d后,2-甲基蒽50μg·L~(-1)处理组对海胆CYP17A1基因的表达表现出抑制作用(P<0.05)。2-甲基蒽对海胆CYP17A1基因表达的影响比苯并(a)芘、3-甲基菲的影响更为明显。

关键词(KeyWords)： 苯并芘;3-甲基菲;2-甲基蒽;中间球海胆;细胞色素CYP17A1;基因表达

Abstract:

Keywords:

基金项目(Foundation): 国家海洋公益性行业科研专项(201305002);; 辽宁省教育厅服务地方项目(DL201804);; 国家海洋局海洋溢油鉴别与损害评估技术重点实验室开放基金资助项目(201309,201809);国家海洋局近岸海域生态环境重点实验室基金资助项目(201013);; 大连海洋大学农业农村部北方海水增养殖重点实验室基金资助项目(2018-KF-21)

作者(Author): 刘帅;宿甜甜;刘长发;魏海峰;赵肖依;宋雪;

Email:

DOI:

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