汪鹏鹏;张松林;靳佳;张敏;

• 1:西北师范大学地理与环境科学学院

摘要(Abstract)：

以辛硫磷和敌百虫为供试毒物,研究其对斑马鱼的单一和联合毒性效应。结果显示,辛硫磷和敌百虫对斑马鱼的96 h半致死浓度(96 h-LC_(50))值分别为6.482 mg·L~(-1)和27.877 mg·L~(-1);按照农药毒性分级标准,辛硫磷对斑马鱼是高毒,敌百虫对斑马鱼是中毒。在辛硫磷和敌百虫联合急性毒性实验中,24、48、72和96 h的相加指数均大于0,表明辛硫磷和敌百虫对斑马鱼的联合毒性为协同效应。采用生化法测定乙酰胆碱酯酶活性发现,乙酰胆碱酯酶活性与辛硫磷、敌百虫以及辛硫磷+敌百虫之间有显著的剂量-效应关系,而且联合作用毒性均大于单一作用毒性。

关键词(KeyWords)： 辛硫磷;敌百虫;斑马鱼;联合毒性;急性毒性;AChE;协同

Abstract:

Keywords:

基金项目(Foundation): 国家自然科学基金(51068025);; 甘肃省自然科学基金项目(1308RJZA302);; 甘肃省油气资源研究重点实验室开放课题基金(SZDKFJJ20150606)

作者(Author): 汪鹏鹏;张松林;靳佳;张敏;

Email:

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