王瀛寰;王会利;张艳峰;刘乐乐;李建中;

• 1:中国科学院生态环境研究中心

摘要(Abstract)：

为研究全氟辛烷磺酸盐(perfluorooctane sulfonate,PFOS)替代品对环境生物的毒害效应,选用中国白羽鹌鹑作为受试生物,建立其环境危害评价毒性测试方法,并对PFOS替代化学品进行了急性经口、急性饲喂及繁殖毒性的风险评价。结果表明,全氟丁基有机铵盐阳离子表面活性剂急性经口毒性实验的LD50为500.44mg·kg-1,其余3种替代化学品在上限浓度2000mg·kg-1,白羽鹌鹑均未出现明显死亡,4种PFOS替代品对中国白羽鹌鹑的急性经口毒性均为低毒。全氟丁基有机铵盐阳离子表面活性剂急性饲喂毒性实验的LC50为970.50mg.kg-1,对白羽鹌鹑的饲喂毒性为中毒,而其余3种替代化学品在上限浓度5000mg·kg-1,白羽鹌鹑均未出现明显死亡,对中国白羽鹌鹑的急性饲喂毒性为低毒。在长期饲喂过程中,织物三防整理剂和C6织物三防整理剂会表现出一定的生殖毒性,造成中国白羽鹌鹑的孵化率降低,胚胎死亡率及未受精率升高;全氟丁基有机铵盐阳离子表面活性剂会影响到中国白羽鹌鹑的未受精率,C4织物三防整理剂未表现出明显的生殖毒性。

关键词(KeyWords)： PFOS替代化学品;中国白羽鹌鹑;急性经口毒性;急性饲喂毒性;繁殖毒性

Abstract:

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基金项目(Foundation): 国家高技术研究发展计划(863)项目(No.2010AA065105和2012AA06A302)

作者(Author): 王瀛寰;王会利;张艳峰;刘乐乐;李建中;

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DOI:

参考文献(References)：

• [1]Clarke B O,Smith S R.Review of emerging'organic contaminants in biosolids and assessment of interna-tional research priorities for the agricultural use of bio-solids[J].Environment International,2011,37(1):226-247
• [2]Directive2006/122/EC of the European Parliament and of the Council of12December2006amending for the30th time Council Directive76/769/EEC on the approximation of the laws,regulations and administra-tive provisions of the Member States relating to re-strictions on the marketing and use of certain danger-ous substances and preparations(perfluorooctane sul-fonates)[OL].http://eur-lex.europa.eu/LexUriServ/LexUriServ.do.uri=CELEX:32006L0122:en:NOT
• [3]朱鲁生.辛硫磷甲氰菊酯及其混剂对鹌鹑的毒性[J].农业环境保护,1999,18(6):258-259
• [4]陈昂,张战泓,刘勇,等.3种植物源农药对鹌鹑和斑马鱼的急性毒性评价[J].安徽农业科学,2010,38(12):6253-6255(in Chinese)Chen Y,Zhang Z H,Liu Y,et al.Acute toxicity evalua-tion of three botanical pesticides to Coturnix coturnix japonica and Brachydonio rerio[J].Journal of Anhui Agricultural Sciences,2010,38(12):6253-6255(in Chinese)
• [5]Unite States Environmental Protection Agency(USE-PA).Ecological Effects Test Guidelines OPPTS850.2100Avian Acute Oral Toxicity Test[S].USEPA,1996
• [6]Organization for Economic Co-operation and Develop-ment(OECD).No.205,OECD Guidelines for the Testing of Chemicals,Avian Dietary Toxicity Test[S].Paris,France:OECD,1984
• [7]蔡道基,杨佩芝,龚瑞忠,等.化学农药环境安全评价试验准则[S].1989,北京:国家环境保护总局,44-48
• [8]李冬.国内主要的鹌鹑品种、品系及配套系[J].河南畜牧兽医,2001,22(10):41-41
• [9]甄莉,贾海燕,陈勇.北京白羽鹌鹑生长性能的测定[J].黑龙江畜牧兽医,2010,(6):148-150
• [10]Unite States Environmental Protection Agency(USE-PA).Ecological Effects Test Guidelines OPPTS850.2200Avian Dietary Toxicity Test[S].USEPA,1996
• [11]Unite States Environmental Protection Agency(USE-PA).Ecological Effects Test Guidelines OPPTS850.2300Avian Reproduction Toxicity Test[S].USEPA,1996
• [12]Organization for Economic Co-operation and Develop-ment(OECD).No.206,OECD Guidelines for the Testing of Chemicals,Avian Reproduction Toxicity Test[S].Paris:OECD,1984