纳米二氧化钛(nTiO_2)与双酚A对斜生栅藻(Scenedes-mus obliquus)的联合毒性效应The Combined Toxic Effect of Nanoscale Titanium Dioxide(nTiO_2) and Bisphenol A( BPA) on Scenedesmus obliquus
赵丽红;朱小山;王一翔;晋慧;王江新;王超;劳永民;姜玥璐;陶益;周进;蔡中华;
摘要(Abstract):
纳米二氧化钛(n Ti O2)在被人们广泛使用的同时,其潜在的环境影响也受到越来越多的关注。为深入探讨n Ti O2与环境中现有污染物的相互作用及生物效应,以斜生栅藻(Scenedesmus obliquus)为受试生物,按照毒性单位法、相加指数法和混合毒性指数法,研究了n Ti O2与双酚A(BPA,一种常见的环境类雌激素)的联合毒性效应。结果显示,n Ti O2与BPA对S.obliquus生长的72 h半抑制浓度(EC50)分别为28.7 mg·L-1与1.81 mg·L-1。而n Ti O2与BPA共存时,在不同毒性比(4:1,3:1,2:1,1:1,1:2和1:3)下,其联合毒性作用(以BPA计)的72 h EC50值分别为2.198,1.58,1.153,0.428,0.306和0.189 mg·L-1。两者的联合毒性作用不仅仅是简单的相加,而是随着两者毒性比的变化,由拮抗作用转变为相加作用,继而转变为协同作用。这表明,n Ti O2进入环境后与现有污染物的毒性比(浓度比)可能是其联合毒性作用模式的一个重要影响因素。
关键词(KeyWords): 纳米二氧化钛;双酚A;斜生栅藻;联合毒性
基金项目(Foundation): 国家自然科学基金资助项目(21107058;41373089);; 环境污染过程与基准教育部重点实验室(南开大学)开放基金资助项目(KLPPEC-2013-01)
作者(Author): 赵丽红;朱小山;王一翔;晋慧;王江新;王超;劳永民;姜玥璐;陶益;周进;蔡中华;
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