徐怀洲;王智志;张圣虎;郭敏;陈玫宏;石利利;

• 1:环境保护部南京环境科学研究所
• 2:深汕特别合作区智慧城市研究院有限公司
• 3:中国药科大学工学院
• 4:贵州大学资源与环境工程学院

摘要(Abstract)：

有机磷酸酯类阻燃剂(organophosphate flame retardants,OPFRs)作为多溴联苯醚等溴代阻燃剂(brominated flame retardants,BFRs)的替代品被广泛应用,由此带来的环境影响广受关注。目前针对OPFRs的生物毒性研究仍相对有限,需要更全面调查其在多环境介质中的暴露状况、环境归趋、生物毒性效应等研究成果,在此基础上才能综合评价其可能引起的生态风险。因此,综述了OPFRs对水生生物、哺乳动物和人类等多种生物体的急性毒性、生殖与发育毒性、神经毒性、脏器毒性、基因毒性与致突变性和内分泌干扰性。OPFRs的多种生物毒性已得到证实,但相关致毒机制研究尚不完整深入。最后对OPFRs的进一步研究存在的问题进行分析,提出了研究展望,以期促进开展OPFRs的环境风险和人体健康风险研究。

关键词(KeyWords)： 有机磷酸酯;阻燃剂;生物毒性

Abstract:

Keywords:

基金项目(Foundation): 国家自然科学基金(21507036);国家自然科学基金(21407055);; 中央级公益性科研院所基本科研业务专项(GYZX170303)

作者(Author): 徐怀洲;王智志;张圣虎;郭敏;陈玫宏;石利利;

Email:

DOI:

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