有机锡致海洋腹足类性畸变分子机制的研究进展Research Progress on Molecular Mechanism of Organotin-Induced Imposex in Marine Gastropods
肖丽萍;王淑红;邹志华;王艺磊;张子平;
摘要(Abstract):
有机锡作为防污损生物附着添加剂曾被大量使用,在极低浓度下就能诱发腹足类发生性畸变现象,严重危害了海洋生态系统的平衡。虽然三丁基锡已被国际海事组织全球禁用,但目前报道的环境有机锡污染仍然非常严重,而且其致毒机制一直众说纷纭。首先,简述了腹足类性畸变及其在世界各个海域有机锡污染监测中的应用,重点综述了有机锡致海洋腹足类性畸变分子机制的3种假说:脊椎动物类型的类固醇激素假说、神经肽假说以及视黄酸X受体(retinoid X receptor,RXR)假说,另外,结合快速发展的分子生物学技术,探讨了研究腹足类性畸变分子机制的新思路和新方法。
关键词(KeyWords): 有机锡;腹足类;性畸变;分子机制
基金项目(Foundation): 国家自然科学基金(20877034);; 福建省科技重点项目(2011N0022);; 国际科学基金(A/4717-1);; 集美大学创新团队基金(2010A001)
作者(Author): 肖丽萍;王淑红;邹志华;王艺磊;张子平;
Email:
DOI:
参考文献(References):
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