部分除草剂与重金属混合物对发光菌的毒性Mixture Toxicity of Herbicides and Heavy Metal Compounds to Photobacteria (Vibrio qinghaiensis sp.—Q67)
宋晓青;刘树深;刘海玲;葛会林;
摘要(Abstract)：
以5种不同类型除草剂和4种重金属为混合物组分,探索混合物毒性变化规律.应用微板毒性分析方法,测定了百草敌、磺草灵、西草净、除草定、环嗪酮、CdCl2·2.5H2O、Ni(NO3)2·6H2O、CoSO4·7H2O和ZnSO4·7H2O对淡水发光菌—青海弧菌Q67(Vibrio qinghaiensis sp.—Q67)的发光抑制毒性.应用非线性最小二乘拟合技术模拟实验剂量-效应数据.结果表明,5种除草剂与4种重金属化合物的剂量-效应曲线(DRC)均可用Weibull函数有效表征.为了全面考察各种不同浓度组成的混合物对Q67的毒性,设计了9个组分同时存在的3个等效应浓度比(EECR)混合物和10个均匀设计浓度比(UDCR)混合物.同样应用微板毒性分析方法测定了各个混合物对Q67的抑制毒性,并应用非线性最小二乘拟合技术模拟了其剂量-效应曲线.通过剂量加和(DA)与独立作用(IA)模型综合分析了各个混合物对发光菌的毒性变化规律.结果表明,不同类型除草剂与多种重金属的各种浓度组合的混合物毒性均可用DA模型进行预测和评估.
关键词(KeyWords)： 青海弧菌;除草剂;重金属;混合物毒性;剂量加和;独立作用
基金项目(Foundation): 国家自然科学基金项目(No. 20577023);; 上海市重点基础研究计划项目(No. 06JC14067);; 全国优秀博士学位论文作者基金项目(No. 200355)
作者(Author): 宋晓青;刘树深;刘海玲;葛会林;
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