石小飞;陈瑞;霍玲玲;赵琳;白茹;让蔚清;陈春英;

• 1:国家纳米科学中心中国科学院纳米生物效应与安全性重点实验室
• 2:南华大学公共卫生学院
• 3:河北师范大学生命科学学院

摘要(Abstract)：

打印机的应用日趋广泛,其释放的颗粒物质尤其是纳米颗粒引起人们的高度关注。现有研究已经证明纳米级颗粒物更容易进入呼吸系统,穿越气血屏障,随之引起机体的氧化损伤、炎症反应和遗传毒性等。打印机释放颗粒的暴露水平评价及其毒理学效应识别是评估打印机健康风险的基础。本文综述了打印机工作场所颗粒暴露水平的监测结果、实验室模拟研究进展、人体采样评价、流行病学调查、体外细胞或整体动物水平毒理学效应评价方法及结果,并提出了打印机危害评估过程的标准化方案建议,以利于不同研究间的比较和总结。

关键词(KeyWords)： 打印机;颗粒物质;现场监测;细胞毒性;炎症反应;基因毒性;氧化损伤

Abstract:

Keywords:

基金项目(Foundation): 科技部“973”项目(2011CB933401,2012CB934003);; “863”项目(2012AA063501);; 国家自然科学基金(21277080);; 湖南省重点学科(公共卫生与预防医学)建设项目

作者(Author): 石小飞;陈瑞;霍玲玲;赵琳;白茹;让蔚清;陈春英;

Email:

DOI:

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