张燕芬;王大勇;

• 1:东南大学发育与疾病相关基因教育部重点实验室

摘要(Abstract)：

模式动物秀丽线虫(Caenorhabditis elegans)在环境科学与生态毒理学研究中发挥着越来越重要的作用,目前利用秀丽线虫已初步建立起较为完善的环境毒物毒性评估体系.该评估体系具体由如下一些指标构成:致死率、最长寿命与半数致死天数、细胞凋亡、个体发育、生殖、运动行为、乙酰胆碱酯酶活性、学习行为、记忆行为、转基因品系、突变体、基因表达模式.论文系统总结了近十多年来利用秀丽线虫进行环境毒物毒性评估的研究体系,并对各个指标的研究方法、研究现状、存在的问题及应用中需要注意的地方进行了讨论。

关键词(KeyWords)： 评估体系;评价指标;环境毒物;秀丽线虫

Abstract:

Keywords:

基金项目(Foundation): 国家自然科学基金项目(No.30771113);; 教育部新世纪优秀人才资助项目

作者(Author): 张燕芬;王大勇;

Email:

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