邻苯二甲酸二乙基己酯(DEHP)毒理与健康效应研究进展Research Advances in Toxicology of DEHP and Its Health Effects
王佳;董四君;
摘要(Abstract):
邻苯二甲酸二乙基己酯(DEHP)作为重要的聚氯乙烯塑料增塑剂在工业上应用广泛。目前,DEHP在海洋、大气、饮用水及动植物体内均被不同程度检出,对生态环境造成日益严重的污染。结合国内外毒理学研究成果,概述DEHP的人体暴露及代谢途径;并从肝脏、心脏、生殖发育系统和呼吸系统等方面详细探讨DEHP对动物健康的危害及其可能的毒性机制,以及对人体健康潜在的影响;在此基础上,对目前存在的问题及进一步研究的方向进行了探讨和展望。
关键词(KeyWords): 邻苯二甲酸二乙基己酯;生殖发育;呼吸系统;健康效应
基金项目(Foundation): 中国科学院百人计划项目(KZCX2-YW-BR-18);; 厦门市科技计划项目(3502Z20112019)
作者(Author): 王佳;董四君;
Email:
DOI:
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